IV Ketamine Therapy

For some individuals living with treatment-resistant depression or other difficult-to-treat psychiatric conditions, traditional treatments may not provide adequate relief. IV ketamine therapy is an evidence-based treatment that may provide rapid symptom improvement for carefully selected patients following a comprehensive psychiatric evaluation. Our providers carefully review your psychiatric history, previous treatments, current medications, and overall medical health to determine whether IV ketamine therapy is an appropriate part of your individualized treatment plan.

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What Is IV Ketamine Therapy?

IV ketamine therapy involves the administration of a carefully controlled, low-dose ketamine infusion in a comfortable clinical setting under the supervision of trained healthcare professionals. Although ketamine is FDA-approved as an anesthetic, IV ketamine infusion therapy for depression is an off-label treatment supported by a growing body of clinical research. Unlike traditional antidepressants, ketamine works through the brain's glutamate system, offering a different treatment approach for carefully selected individuals. Every infusion is administered with continuous monitoring to help ensure your safety and comfort throughout treatment.

A growing body of clinical research supports IV ketamine therapy as a treatment option for carefully selected individuals with treatment-resistant depression who have not experienced adequate improvement with conventional therapies.

Evidence-Based Treatment

Every patient begins with a comprehensive psychiatric evaluation. Treatment recommendations are based on your psychiatric diagnosis, medical history, previous treatment response, current medications, and overall clinical needs to determine whether IV ketamine therapy is appropriate.

Individualized Care

Each infusion is administered in a comfortable clinical setting with continuous monitoring of your vital signs by trained healthcare professionals. Your safety, comfort, and overall treatment experience remain our highest priorities throughout every visit.

Carefully Monitored

Who May Benefit from IV Ketamine Therapy?

IV ketamine therapy is not appropriate for everyone experiencing depression. Every patient undergoes a comprehensive psychiatric evaluation to confirm the diagnosis, review previous treatments, assess medical and psychiatric history, and determine whether IV ketamine therapy may be an appropriate part of an individualized treatment plan.

IV ketamine therapy may be appropriate for adults with treatment-resistant depression who have not experienced adequate improvement despite appropriate trials of traditional antidepressant medications or who require an alternative treatment approach after careful evaluation.

Treatment-Resistant Depression

Every patient begins with a comprehensive psychiatric evaluation. Treatment recommendations are based on your diagnosis, medical history, previous treatment response, current medications, and overall clinical needs to determine whether IV ketamine therapy is appropriate.

Previous Medication Challenges

Not everyone with depression is a candidate for IV ketamine therapy. A comprehensive psychiatric evaluation helps ensure treatment recommendations are safe, appropriate, and tailored to your diagnosis, medical history, treatment goals, and overall clinical needs.

Comprehensive Evaluation Required

What to Expect During Treatment

Every patient begins with a comprehensive psychiatric evaluation before IV ketamine therapy is considered. If treatment is appropriate, our team will guide you through every stage of care—from your initial consultation and induction series to ongoing progress assessments and maintenance treatment when clinically indicated.

Step 1

Before beginning IV ketamine therapy, you'll meet with one of our psychiatric providers for a comprehensive evaluation. We'll review your symptoms, treatment history, medical history, current medications, and treatment goals to determine whether IV ketamine therapy is an appropriate treatment option.

Comprehensive Psychiatric Evaluation

Step 2

If IV ketamine therapy is recommended, we'll develop an individualized treatment plan based on your diagnosis, current symptoms, previous treatment response, and overall clinical needs. We'll also review the treatment process, answer your questions, and discuss what to expect before your first infusion.

Individualized Treatment Planning

Step 3

Most patients begin with an induction series consisting of six IV ketamine infusions administered over approximately two to three weeks. Although treatment schedules may vary based on individual clinical needs, this structured induction series is designed to provide the best opportunity for symptom improvement while allowing your provider to monitor your progress throughout therapy.

Induction Series

Step 4

Each treatment is administered in a comfortable clinical setting over approximately 40 minutes. Throughout your infusion, our clinical team continuously monitors your blood pressure, heart rate, oxygen saturation, and overall comfort

Infusion Appointments

Step 5

Throughout treatment, your provider will regularly assess your symptoms using validated clinical rating scales, review your response to therapy, and discuss any changes in your symptoms or treatment goals. These assessments help guide individualized treatment recommendations throughout your course of care.

Ongoing Progress Monitoring

Step 6

Following completion of the induction series, some patients benefit from maintenance or booster infusions based on symptom recurrence, treatment response, and clinical judgment. Your provider will discuss whether additional treatments may be appropriate as part of your long-term treatment plan.

Maintenance or Booster Infusions

Why an Induction Series?

IV ketamine therapy is typically delivered as a series of treatments rather than a single infusion. Research and clinical experience have shown that an induction series provides the best opportunity for meaningful, lasting symptom improvement in many patients with treatment-resistant depression.

Throughout the induction series, your provider monitors your response, evaluates symptom improvement using clinical assessments, and adjusts your individualized treatment plan as needed. This process helps determine whether additional maintenance or booster infusions may be beneficial based on your progress and long-term treatment goals.

Preparing for Your Treatment

Preparing for your IV ketamine infusion is simple. Our team will provide detailed instructions before your first appointment and answer any questions you may have. Following these recommendations helps ensure your treatment is as safe and comfortable as possible.

  • Continue taking your prescribed medications unless your provider gives you different instructions.

  • Do not eat for at least 2 hours before your infusion.

  • You may drink clear liquids until 30 minutes before your appointment.

  • Wear comfortable clothing and consider bringing headphones, music, or another relaxing activity.

  • Arrange for a responsible adult to drive you home. Patients may not drive after treatment until the following day after a restful night's sleep.

Before Your Appointment

  • Your IV ketamine infusion is administered over approximately 40–45 minutes in a comfortable treatment room.

  • Our clinical team continuously monitors your blood pressure, heart rate, oxygen level, and overall comfort throughout your treatment.

  • Many patients experience temporary changes in perception, relaxation, or dissociation during the infusion. These effects are expected and typically resolve before discharge.

  • Your provider and treatment team remain with you throughout the visit to ensure your comfort and safety.

During Your Infusion

After Your Treatment

  • You'll remain under observation until your provider determines it is safe for discharge.

  • A responsible adult must drive you home following every infusion.

  • Do not drive, operate machinery, or make important decisions until the following day after a restful night's sleep.

  • Plan to rest for the remainder of the day and follow all discharge instructions provided by your treatment team.

  • Contact our office if you have questions or concerns after your treatment.

Every patient's response to IV ketamine therapy is unique. Before your first infusion, we'll review the treatment process, discuss what you may experience during and after treatment, answer your questions, and help ensure you feel informed and comfortable throughout your care.

Safety & Monitoring

Patient safety is our highest priority throughout every stage of IV ketamine therapy. Before treatment begins, every patient undergoes a comprehensive psychiatric evaluation and medical screening to determine whether IV ketamine therapy is appropriate. During each infusion, our clinical team continuously monitors your vital signs, comfort, and overall condition to help ensure treatment is delivered safely and effectively.

Before recommending IV ketamine therapy, we carefully review your psychiatric history, medical history, previous treatments, current medications, and treatment goals. This comprehensive evaluation helps determine whether IV ketamine therapy is appropriate and allows us to develop an individualized treatment plan tailored to your needs.

Comprehensive Medical Evaluation

Throughout every infusion, our clinical team continuously monitors your blood pressure, heart rate, oxygen saturation, and overall comfort. A trained healthcare professional remains available throughout your treatment, and your recovery is assessed before you're discharged home.

Continuous Monitoring

Treatment doesn't end when your infusion is complete. We regularly assess your symptoms, monitor your response to treatment, review any side effects, and adjust your treatment plan when clinically appropriate to support lasting improvement.

Individualized Follow-Up

Our goal is to provide safe, evidence-based IV ketamine therapy while ensuring every patient feels informed, comfortable, and supported throughout every stage of care.

Treatment Costs & Payment

We believe every patient should have a clear understanding of treatment costs before beginning care. Because IV ketamine therapy for psychiatric conditions is generally not covered by most commercial insurance plans, Medicare, or Ohio Medicaid, treatment is offered as a self-pay service at our practice.

Most patients begin with six IV ketamine infusions completed over approximately 2–3 weeks.

Package Price: $1,350

Average Cost: $225 per infusion

The induction package includes:

  • Comprehensive psychiatric evaluation

  • Individualized treatment planning

  • Six monitored IV ketamine infusions

  • Continuous vital sign monitoring

  • Ongoing symptom assessments and clinical follow-up

Induction Series

Following completion of the induction series, some patients benefit from maintenance or booster infusions based on symptom recurrence, treatment response, and clinical judgment. If additional treatment is recommended, your provider will discuss an individualized maintenance schedule and associated costs before treatment is scheduled.

Maintenance Treatments

Your treatment plan, expected costs, and applicable office policies will be reviewed before treatment begins. We believe in transparent pricing without hidden fees so you can make an informed decision about your care.

Clear, Upfront Pricing

IV ketamine therapy for depression is considered an off-label use of an FDA-approved medication. Because of this, most insurance plans do not provide coverage for psychiatric IV ketamine infusions. During your evaluation, your provider will discuss all clinically appropriate treatment options—including insurance-covered treatments such as Spravato® or Transcranial Magnetic Stimulation (TMS)—when appropriate.

Frequently Asked Questions

  • IV ketamine therapy involves the administration of a carefully controlled, low-dose ketamine infusion under the supervision of trained healthcare professionals. Ketamine works differently than traditional antidepressants and may be an appropriate treatment option for certain individuals with treatment-resistant depression following a comprehensive psychiatric evaluation.

  • Every patient begins with a comprehensive psychiatric evaluation. During this appointment, your provider will review your symptoms, previous treatments, medical history, current medications, and treatment goals to determine whether IV ketamine therapy is an appropriate option.

  • Although both treatments are derived from ketamine and may be used for treatment-resistant depression, they are administered differently and have different regulatory requirements. Spravato® is an FDA-approved intranasal medication available only through a REMS-certified program, while IV ketamine is administered by intravenous infusion. During your evaluation, your provider will discuss which treatment, if any, is most appropriate for your individual needs.

  • IV ketamine therapy is typically delivered as a series of treatments rather than a single infusion. An induction series allows your provider to monitor your response over time, assess symptom improvement, and develop an individualized long-term treatment plan based on your clinical progress.

  • The ketamine infusion itself is administered over approximately 40 minutes. Including preparation, monitoring, and recovery, you should plan to be in the office for approximately 90 to 120 minutes for each appointment.

  • Yes. Patients remain awake throughout treatment. Many individuals experience temporary changes in perception, relaxation, or dissociation during the infusion, but our clinical team remains with you and continuously monitors your treatment throughout the visit.

  • No. Because ketamine can temporarily affect judgment, coordination, and reaction time, you must arrange for a responsible adult to drive you home following every infusion. Do not drive, operate heavy machinery, or make important decisions until the following day after a restful night's sleep.

  • Every patient's response is different. Some individuals notice changes early in treatment, while others experience more gradual improvement throughout the induction series. Your provider will regularly assess your progress and discuss your response throughout treatment.

  • Common side effects may include temporary dissociation, dizziness, nausea, blurred vision, elevated blood pressure, or changes in perception during treatment. These effects typically resolve before you leave the office, and our clinical team continuously monitors you throughout every infusion.

  • Most commercial insurance plans, Medicare, and Ohio Medicaid do not currently cover IV ketamine infusions for the treatment of depression. Because of this, IV ketamine therapy is offered as a self-pay service at our practice.

  • We believe financial considerations should not be an unnecessary barrier to evidence-based mental health care. Our practice is intentionally designed to provide high-quality psychiatric care in an efficient outpatient setting while maintaining the same commitment to patient safety, individualized treatment planning, continuous clinical monitoring, and ongoing psychiatric follow-up. Our focus is delivering exceptional clinical care at a transparent and competitive price.

  • Treatment-resistant depression is often a chronic condition, and every patient's course is different. While some individuals experience sustained improvement after completing the induction series, others may benefit from maintenance infusions based on symptom recurrence and clinical response. Your provider will work with you to develop an individualized long-term treatment plan and determine whether maintenance therapy is appropriate.

  • IV ketamine therapy is not appropriate for everyone. Certain medical and psychiatric conditions may make treatment inappropriate or require additional evaluation before therapy begins. During your comprehensive psychiatric evaluation, your provider will review your medical history, current medications, and overall health to determine whether IV ketamine therapy is a safe and appropriate treatment option.

  • The first step is to request a comprehensive psychiatric evaluation. During this appointment, your provider will review your symptoms, treatment history, medical history, and treatment goals to determine whether IV ketamine therapy is appropriate. If recommended, our team will guide you through every step of treatment, from your induction series to ongoing follow-up and maintenance planning.

If you've been living with treatment-resistant depression despite trying traditional treatments, you don't have to navigate the next steps alone. Our team provides comprehensive psychiatric evaluations to determine whether IV ketamine therapy—or another evidence-based treatment—is appropriate for your individual needs. We'll take the time to understand your history, answer your questions, and develop a personalized treatment plan focused on helping you achieve meaningful, lasting improvement.

Ready to Learn Whether IV Ketamine Therapy Is Right for You?

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Compassionate care. Evidence-based treatment. Personalized for every patient.

Helping individuals and families throughout Beavercreek, Dayton, and Southwest Ohio find the right path forward.